Switching from Mounjaro to Wegovy
- Wegovy is now licensed for cardiovascular risk reduction - this may make more sense for you.
- Mounjaro and Wegovy are both highly effective medications for weight management.
- Our UK-based clinical team can support your switch from Mounjaro to Wegovy.
Wegovy vs Mounjaro
Avg. weight loss
Up to ~21%
Avg. weight loss
Up to ~22%
Active Ingredient
Semaglutide
Active Ingredient
Tirzepatide
How It Works
GLP-1 receptor agonist (single hormone)
How It Works
Dual GLP-1 & GIP receptor agonist (two hormones)
Dose Flexibility
Adjusted according to clinical response
Dose Flexibility
Adjusted according to clinical response
Suitable with oral contraception?
Yes
Suitable with oral contraception?
No
Injection Site Reactions
0.3% of patients
Injection Site Reactions
8.6% of patients
Licensed For
Weight management & cardiovascular risk reduction
Licensed For
Weight management & type 2 diabetes
Comparing doses
You don’t need to start over. Our clinicians can help find you a suitable Wegovy dose based on your current Mounjaro dose and tolerance. Select your current Mounjaro dose to see the equivalent Wegovy dose.
Select your current Mounjaro dosage
Wegovy Dosage & Pricing
- 7 day wash-out period between your first dose of Wegovy and last dose of Mounjaro
- Our prescribers will assess each case individually before making a recommendation.
Wegovy Dosage & Pricing
- 7 day wash-out period between your first dose of Wegovy and last dose of Mounjaro
- Our prescribers will assess each case individually before making a recommendation.
Wegovy Dosage & Pricing
- 7 day wash-out period between your first dose of Wegovy and last dose of Mounjaro
- Our prescribers will assess each case individually before making a recommendation.
Wegovy Dosage & Pricing
- 7 day wash-out period between your first dose of Wegovy and last dose of Mounjaro
- Our prescribers will assess each case individually before making a recommendation.
Wegovy Dosage & Pricing
- 7 day wash-out period between your first dose of Wegovy and last dose of Mounjaro
- Our prescribers will assess each case individually before making a recommendation.
Wegovy Dosage & Pricing
- 7 day wash-out period between your first dose of Wegovy and last dose of Mounjaro
- Our prescribers will assess each case individually before making a recommendation.
How do I switch from Mounjaro to Wegovy?
Frequently asked questions
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Why has the price of Mounjaro changed?
The price of Mounjaro increased in September 2025 following a decision by its manufacturer, Eli Lilly. When Mounjaro first launched in the UK, it was deliberately priced lower than in other countries to help as many patients as possible access the treatment. Eli Lilly has since raised UK prices to bring them in line with what patients pay in Europe, the United States, and other developed countries. This decision was made solely by the manufacturer and affects every provider in the UK equally — including pharmacies, private clinics, and online platforms.
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Why are people switching from Mounjaro to Wegovy?
There are several reasons why patients move from Mounjaro to Wegovy. The most common include cost, as Mounjaro tends to be more expensive particularly at higher doses. Some patients also switch due to Mounjaro stock shortages, side effect tolerability, or because their prescriber recommends Wegovy based on their individual health profile — particularly for patients with established cardiovascular disease, where Wegovy has strong supporting outcomes data from the SELECT trial.
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Is Wegovy as effective as Mounjaro in the long term?
Based on current clinical trial data, Mounjaro produces greater average weight loss than Wegovy. Patients on Mounjaro lost an average of up to 22.5% of their body weight in trials, compared to approximately 21% with Wegovy 7.2mg. Switching from Mounjaro to Wegovy may therefore result in a slower rate of weight loss or a plateau, and some patients may experience modest weight regain during the transition. However, Wegovy remains a highly effective weight loss treatment in its own right.
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Will I gain weight when switching from Mounjaro to Wegovy?
There is a possibility of some weight regain during the transition period, particularly during the Wegovy dose escalation phase. During this period the appetite-suppressing effect may be lower than you were used to on your maintenance dose of Mounjaro. Maintaining your dietary and lifestyle habits during the switch is therefore very important.
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When should I take my first Wegovy dose after stopping Mounjaro?
As both Mounjaro and Wegovy are once-weekly injections, you should take your first Wegovy injection in place of your next scheduled Mounjaro dose. There is no washout period required between the two treatments. Your prescriber at HEBA Online Pharmacy will confirm the exact timing as part of your clinical review.
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Will the side effects be different on Wegovy compared to Mounjaro?
Both medications share similar gastrointestinal side effects including nausea, vomiting, diarrhoea, and constipation. However, some patients who experienced more pronounced side effects on Mounjaro find Wegovy better tolerated, as Mounjaro's additional GIP receptor activity can amplify these effects in some individuals. Conversely, patients who tolerated Mounjaro well may find the side effect profile of Wegovy broadly similar.
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Can I switch back to Mounjaro from Wegovy in the future?
Yes, switching back to Mounjaro is possible if clinically appropriate.
Meet the people behind the pharmacy
At Heba Online Pharmacy, your health and safety are our top priorities. Our team of specialist pharmacists brings years of experience and a deep commitment to providing reliable, personalised care.
Ubayd Ali
Superintendent Pharmacist
Sufyan Tahir
Lead Clinical Pharmacist